SB-674042
SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd=5.03 nM), exhibits 100-fold selectivity for OX1 over OX2 receptors with IC50 values of 3.76 nM and 531 nM, respectively.
| Catalog Number | E8005 |
| Molecular Formula | C18H20N2O3 |
| CAS# | 483313-22-0 |
| Inchi | InChI=1S/C18H20N2O3/c1-12(2)16(13-6-4-3-5-7-13)18(22)19-15-10-8-14(9-11-15)17(21)20-23/h3-12,16,23H,1-2H3,(H,19,22)(H,20,21)/t16-/m0/s1 |
| Inchi Key | LAMIXXKAWNLXOC-INIZCTEOSA-N |
| SMILES | CC(C)C(C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sb-674042.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8005-sb-674042-chemical-structure-tube.png |