Buloxibutid
Buloxibutid (AT2 Agonist C21) is a selective agonist of angiotensin II type 2 receptor (AT2R) with a Ki value of 0.4 nM for the AT2 receptor and a Ki >10 µM for the AT1 receptor. Its treatment significantly reduces vascular remodelling, improves hemodynamics, and decreases pulmonary collagen deposition in the Sugen-Hypoxia model of pulmonary hypertension.
| Trivial name | AT2 Agonist C21 |
| Catalog Number | E4616 |
| Molecular Formula | C11H15ClN4O4 |
| CAS# | 477775-14-7 |
| SMILES | C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N.Cl |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/buloxibutid.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4616-Buloxibutid-chemical-structure.png |