PHA-665752
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9 nM in cell-free assays, >50-fold selectivity for c-Met than RTKs or STKs.
| Trivial name | N/A |
| Catalog Number | S1070 |
| Molecular Formula | C32H34Cl2N4O4S |
| CAS# | 477575-56-7 |
| Inchi | InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17 -18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1 |
| Inchi Key | OYONTEXKYJZFHA-SSHUPFPWSA-N |
| SMILES | CC1=C(NC(=C1C(=O)N2CCCC2CN3CCCC3)C)C=C4C5=C(C=CC(=C5)S(=O)(=O)CC6=C(C=CC=C6Cl)Cl)NC4=O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/PHA-665752.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PHA-665752-chemical-structure-S1070.gif |