Dehydrocostus Lactone
Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
| Trivial name | N/A |
| Catalog Number | S3615 |
| Molecular Formula | C25H31N3O5S2 |
| CAS# | 477-43-0 |
| Inchi | InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2 |
| Inchi Key | JLCFMMIWBSZOIS-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)NS(=O)(=O)C2=CC3=C(C=C2)C4=C(C3=NO)C=C(C=C4)S(=O)(=O)NC5CCCCC5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/dehydrocostus-lactone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/dehydrocostus-lactone-chemical-structure-s3615.gif |
