NVP-AEW541
NVP-AEW541 is a potent inhibitor of IGF-1R/InsR with IC50 of 150 nM/140 nM in cell-free assays, greater potency and selectivity for IGF-1R in a cell-based assay.
| Trivial name | AEW541 |
| Catalog Number | S1034 |
| Molecular Formula | C27H29N5O |
| CAS# | 475489-16-8 |
| Inchi | InChI=1S/C27H29N5O/c28-26-25-24(21-8-4-9-23(14-21)33-17-19-6-2-1-3-7-19)16-32(27(25)30-18-29-26)22-12-20(13-22)15-31-10-5-11-31/h1-4,6-9,14,16,18,20,22H,5,10-13,15,17H2,(H2,28,29,30)/t20-,22+ |
| Inchi Key | AECDBHGVIIRMOI-GRGXKFILSA-N |
| SMILES | C1CN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/NVP-AEW541.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NVP-AEW541-chemical-structure-S1034.gif |