Tivozanib

Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.

Price Not Available 5mg Tivozanib Supplier Page
Trivial name AV-951, KRN-951
Catalog Number S1207
Molecular Formula C22H19ClN4O5
CAS# 475108-18-0
Inchi InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)
Inchi Key SPMVMDHWKHCIDT-UHFFFAOYSA-N
SMILES CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
Size 5mg
Supplier Page http://www.selleckchem.com/products/AV-951.html
Additional Information https://file.selleck.cn/downloads/struct/AV-951-Tivozanib-chemical-structure-S1207.gif