(+)-Isocorynoline
Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.
| Trivial name | N/A |
| Catalog Number | S9258 |
| Molecular Formula | C20H23NO4 |
| CAS# | 475-67-2 |
| Inchi | InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)20(25-4)18-16(12)13(21)9-11-5-6-14(23-2)19(22)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1 |
| Inchi Key | QELDJEKNFOQJOY-ZDUSSCGKSA-N |
| SMILES | CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)OC)OC |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/isocorynoline.html |
| Additional Information | https://file.selleck.cn/downloads/struct/isocorynoline-chemical-structure-s9258.gif |