AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively.
Trivial name | N/A |
Catalog Number | S8682 |
Molecular Formula | C32H28F3N5O4 |
CAS# | 473719-41-4 |
SMILES | CCOC1=CC=C(C=C1)N2C(=O)C3=CC=CN=C3N=C2C(C)N(CC4=CC=CN=C4)C(=O)CC5=CC=C(OC(F)(F)F)C=C5 |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/amg-487.html |
Additional Information | https://file.selleck.cn/downloads/struct/s8682-amg487-chemical-structure.gif |