NR2B-selective NMDA receptor antagonist 1 | MedChemExpress (MCE)

NR2B-selective NMDA receptor antagonist 1 (compound 29) is a potent antagonist of NR1/NR2B receptors, with IC50s of 0.05 μM, 0.73 μM, 2.4 μM to NR1/NR2B NMDA receptor, hERG, α1-AdR, respectivity. NR2B-selective NMDA receptor antagonist 1 exhibites efficient permeability across the blood–brain barrier[1].

Trivial name NR2B-selective NMDA receptor antagonist 1
Catalog Number HY-126123
Research Area Neurological Disease
CAS# 457897-92-6
Purity ≥98.0%
SMILES CS(NC1=CC=C(C=C1)OC[C@@H](O)CNCCC2=CC(Cl)=C(C=C2)Cl)(=O)=O
Size 1 mg
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