GW788388
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM in a cell-free assay, also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor.
| Trivial name | N/A |
| Catalog Number | S2750 |
| Molecular Formula | C25H23N5O2 |
| CAS# | 452342-67-5 |
| Inchi | InChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31) |
| Inchi Key | SAGZIBJAQGBRQA-UHFFFAOYSA-N |
| SMILES | C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gw788388.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GW788388-chemical-structure-s2750.gif |