ZM 449829

ZM 449829 is a potent and selective inhibitor of Janus tyrosine kinase 3 (JAK3) which binds competitively to the JAK3 ATP site (pIC50 = 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4, respectively). ZM 449829 inhibits STAT-5 phosphorylation and T cell proliferation.

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Catalog Number	4452-06-6
Alternative Name(s)	ZM 449829; ZM449829; ZM-449829; 1-(2-Naphthalenyl)-2-propen-1-one; JAK3 inhibitor V
Molecular Formula	C13H10O
CAS#	4452-06-6
Purity	≥98%
Inchi	InChI=1S/C13H10O/c1-2-13(14)12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
Inchi Key	FOTCGZPFSUWZBN-UHFFFAOYSA-N
Size	Please inquire
Supplier Page	https://www.bocsci.com/zm-449829-cas-4452-06-6-item-77665.html