Macitentan
Macitentan is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM.
| Trivial name | ACT 064992 |
| Catalog Number | S8051 |
| Molecular Formula | C19H20Br2N6O4S |
| CAS# | 441798-33-0 |
| Inchi | InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27) |
| Inchi Key | JGCMEBMXRHSZKX-UHFFFAOYSA-N |
| SMILES | CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/macitentan.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Macitentan-chemical-structure-s8051.gif |