Kobe0065
Kobe0065 is an H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.
| Trivial name | N/A |
| Catalog Number | S8303 |
| Molecular Formula | C15H11ClF3N5O4S |
| CAS# | 436133-68-5 |
| Inchi | InChI=1S/C15H11ClF3N5O4S/c1-7-2-3-9(6-10(7)16)20-14(29)22-21-13-11(23(25)26)4-8(15(17,18)19)5-12(13)24(27)28/h2-6,21H,1H3,(H2,20,22,29) |
| Inchi Key | KSJVAYBCXSURMQ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/kobe0065.html |
| Additional Information | https://file.selleck.cn/downloads/struct/kobe0065-chemical-structure-s8303.gif |