VU 0357121
VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM, is inactive or very weakly antagonizing at other mGlu receptor subtypes.
| Trivial name | N/A |
| Catalog Number | S2795 |
| Molecular Formula | C17H17F2NO2 |
| CAS# | 433967-28-3 |
| Inchi | InChI=1S/C17H17F2NO2/c1-2-3-10-22-14-7-4-12(5-8-14)17(21)20-16-9-6-13(18)11-15(16)19/h4-9,11H,2-3,10H2,1H3,(H,20,21) |
| Inchi Key | AHCYOTLTLQTPSU-UHFFFAOYSA-N |
| SMILES | CCCCOC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)F)F |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/vu-0357121.html |
| Additional Information | https://file.selleck.cn/downloads/struct/vu-0357121-chemical-structure-s2795.gif |