Sotrastaurin (AEB071)
Sotrastaurin (AEB071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2791 |
| Molecular Formula | C26H24N6O2S2 |
| CAS# | 425637-18-9 |
| Inchi | InChI=1S/C26H24N6O2S2/c1-17-23(36-25(28-17)18-5-4-8-27-13-18)24(33)29-21-7-3-2-6-20(21)22-15-32-19(16-35-26(32)30-22)14-31-9-11-34-12-10-31/h2-8,13,15-16H,9-12,14H2,1H3,(H,29,33) |
| Inchi Key | LAMQVIQMVKWXOC-UHFFFAOYSA-N |
| SMILES | CC1=C(SC(=N1)C2=CN=CC=C2)C(=O)NC3=CC=CC=C3C4=CN5C(=CSC5=N4)CN6CCOCC6 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sotrastaurin-aeb071.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Sotrastaurin-AEB071-chemical-structure-s2791.gif |