Sotrastaurin (AEB071)
Sotrastaurin (AEB071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2791 |
| Molecular Formula | C19H25ClN6O |
| CAS# | 425637-18-9 |
| Inchi | InChI=1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1 |
| Inchi Key | PMXCMJLOPOFPBT-HNNXBMFYSA-N |
| SMILES | CC(C)C(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC=C3)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/sotrastaurin-aeb071.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Sotrastaurin-AEB071-chemical-structure-s2791.gif |