Hesperadin
Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.
| Trivial name | N/A |
| Catalog Number | S1529 |
| Molecular Formula | C29H32N4O3S |
| CAS# | 422513-13-1 |
| Inchi | InChI=1S/C29H32N4O3S/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32H,2,4,7-8,17-18,20H2,1H3,(H,31,34)/b28-27 - |
| Inchi Key | GLDSKRNGVVYJAB-DQSJHHFOSA-N |
| SMILES | CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=C2C(=NC3=CC=C(C=C3)CN4CCCCC4)C5=CC=CC=C5)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Hesperadin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Hesperadin-chemical-structure-S1529.gif |