Carboplatin
Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell’s repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
| Trivial name | NSC 241240, JM-8, CBDCA |
| Catalog Number | S1215 |
| Molecular Formula | C15H19N5 |
| CAS# | 41575-94-4 |
| Inchi | InChI=1S/C15H19N5/c1-19-7-9-20(10-8-19)14-11-13(17-15(16)18-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H2,16,17,18) |
| Inchi Key | NIJGWJIOMPHDBP-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C2=NC(=NC(=C2)C3=CC=CC=C3)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Carboplatin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Carboplatin-chemical-structure-S1215.gif |