Carboplatin
Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell’s repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
| Trivial name | NSC 241240, JM-8, CBDCA |
| Catalog Number | S1215 |
| Molecular Formula | C6H12N2O4Pt |
| CAS# | 41575-94-4 |
| Inchi | InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2 |
| Inchi Key | OLESAACUTLOWQZ-UHFFFAOYSA-L |
| SMILES | C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2] |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/Carboplatin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Carboplatin-chemical-structure-S1215.gif |