Rac-Belinostat
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.

Catalog Number | T1852 |
Alternative Name(s) | PXD101 , NSC726630 , PX-105684 |
Research Area | DNA Damage/DNA Repair|||Chromatin/Epigenetic |
Molecular Formula | C15H14N2O4S |
CAS# | 414864-00-9 |
Purity | 99.93% |
SMILES | ONC(=O)/C=C/c1cc(ccc1)S(=O)(=O)Nc1ccccc1 |
Size | 5 mg |
Supplier Page | https://www.targetmol.com/compound/Belinostat |
Additional Information | https://www.targetmol.com/datasheet/T1852 |