Belinostat
Belinostat is a novel HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors. Belinostat (PXD101) induces autophagy.
| Trivial name | PXD101,NSC726630, PX-105684 |
| Catalog Number | S1085 |
| Molecular Formula | C15H14N2O4S |
| CAS# | 866323-14-0 |
| Inchi | InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+ |
| Inchi Key | NCNRHFGMJRPRSK-MDZDMXLPSA-N |
| SMILES | C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)C=CC(=O)NO |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Belinostat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Belinostat-PXD101-chemical-structure-S1085.gif |