4-IPP
4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) and a specific suicide substrate for MIF. 4-IPP can inhibit receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis and potentiate osteoblast-mediated mineralization and bone nodule formation in vitro.
| Trivial name | 4-Iodo-6-phenylpyrimidine |
| Catalog Number | S2643 |
| Molecular Formula | C17H15N9 |
| CAS# | 41270-96-6 |
| Inchi | InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1 |
| Inchi Key | XYDNMOZJKOGZLS-NSHDSACASA-N |
| SMILES | CC(C1=CN2C=CN=C2C=C1)N3C4=NC(=CN=C4N=N3)C5=CN(N=C5)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/4-ipp.html |
| Additional Information | https://file.selleck.cn/downloads/struct/4-ipp-chemical-structure-s2643.gif |