4-IPP
4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) and a specific suicide substrate for MIF. 4-IPP can inhibit receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis and potentiate osteoblast-mediated mineralization and bone nodule formation in vitro.
| Trivial name | 4-Iodo-6-phenylpyrimidine |
| Catalog Number | S2643 |
| Molecular Formula | C10H7IN2 |
| CAS# | 41270-96-6 |
| Inchi | InChI=1S/C10H7IN2/c11-10-6-9(12-7-13-10)8-4-2-1-3-5-8/h1-7H |
| Inchi Key | ZTCJXHNJVLUUMR-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=CC(=NC=N2)I |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/4-ipp.html |
| Additional Information | https://file.selleck.cn/downloads/struct/4-ipp-chemical-structure-s2643.gif |