SB590885
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM in a cell-free assay, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.
| Trivial name | N/A |
| Catalog Number | S2220 |
| Molecular Formula | C27H27N5O2 |
| CAS# | 405554-55-4 |
| Inchi | InChI=1S/C27H27N5O2/c1-32(2)15-16-34-22-7-3-19(4-8-22)27-29-25(18-11-13-28-14-12-18)26(30-27)21-5-9-23-20(17-21)6-10-24(23)31-33/h3-5,7-9,11-14,17,33H,6,10,15-16H2,1-2H3,(H,29,30)/b31-24+ |
| Inchi Key | MLSAQOINCGAULQ-QFMPWRQOSA-N |
| SMILES | CN(C)CCOC1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC5=C(C=C4)C(=NO)CC5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/SB590885.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB590885-chemical-structure-S2220.gif |