SB590885
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM in a cell-free assay, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.
| Trivial name | N/A |
| Catalog Number | S2220 |
| Molecular Formula | C27H28N2O3 |
| CAS# | 405554-55-4 |
| Inchi | InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30) |
| Inchi Key | SHHUPGSHGSNPDB-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/SB590885.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB590885-chemical-structure-S2220.gif |