Salubrinal
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM in a cell-free assay.
Trivial name | N/A |
Catalog Number | S2923 |
Molecular Formula | C21H17Cl3N4OS |
CAS# | 405060-95-9 |
Inchi | InChI=1S/C21H17Cl3N4OS/c22-21(23,24)19(27-17(29)12-11-14-6-2-1-3-7-14)28-20(30)26-16-10-4-8-15-9-5-13-25-18(15)16/h1-13,19H,(H,27,29)(H2,26,28,30)/b12-11+ |
Inchi Key | LCOIAYJMPKXARU-VAWYXSNFSA-N |
SMILES | C1=CC=C(C=C1)C=CC(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3 |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/salubrinal.html |
Additional Information | https://file.selleck.cn/downloads/struct/Salubrinal-chemical-structure-s2923.jpg |