Panobinostat (LBH589)
Panobinostat (LBH589, NVP-LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. Panobinostat (LBH589) induces autophagy and apoptosis. Panobinostat effectively disrupts HIV latency in vivo. Phase 3.
Trivial name | NVP-LBH589 |
Catalog Number | S1030 |
Molecular Formula | C21H23N3O2 |
CAS# | 404950-80-7 |
Inchi | InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+ |
Inchi Key | FPOHNWQLNRZRFC-ZHACJKMWSA-N |
SMILES | CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/LBH-589.html |
Additional Information | https://file.selleck.cn/downloads/struct/LBH-589-Panobinostat-chemical-structure-S1030.gif |