PHA-680632
PHA-680632 is a potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Trivial name | N/A |
Catalog Number | S1454 |
Molecular Formula | C23H26N2O4 |
CAS# | 398493-79-3 |
Inchi | InChI=1S/C23H26N2O4/c1-16-13-18-7-5-6-8-19(18)25(16)12-11-24-22(26)10-9-17-14-20(27-2)23(29-4)21(15-17)28-3/h5-10,13-15H,11-12H2,1-4H3,(H,24,26)/b10-9+ |
Inchi Key | YBHUXHFZLMFETJ-MDZDMXLPSA-N |
SMILES | CC1=CC2=CC=CC=C2N1CCNC(=O)C=CC3=CC(=C(C(=C3)OC)OC)OC |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/PHA-680632.html |
Additional Information | https://file.selleck.cn/downloads/struct/PHA-680632-chemical-structure-S1454.gif |