PHA-680632
PHA-680632 is a potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
| Trivial name | N/A |
| Catalog Number | S1454 |
| Molecular Formula | C28H35N7O2 |
| CAS# | 398493-79-3 |
| Inchi | InChI=1S/C28H35N7O2/c1-4-19-7-6-8-20(5-2)25(19)29-28(37)35-17-23-24(18-35)31-32-26(23)30-27(36)21-9-11-22(12-10-21)34-15-13-33(3)14-16-34/h6-12H,4-5,13-18H2,1-3H3,(H,29,37)(H2,30,31,32,36) |
| Inchi Key | OBWNXGOQPLDDPS-UHFFFAOYSA-N |
| SMILES | CCC1=C(C(=CC=C1)CC)NC(=O)N2CC3=C(C2)NN=C3NC(=O)C4=CC=C(C=C4)N5CCN(CC5)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/PHA-680632.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PHA-680632-chemical-structure-S1454.gif |