Tandutinib (MLN518)

Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.

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Trivial name	CT 53518, NSC726292, MLN518
Catalog Number	S1043
Molecular Formula	C21H28O2
CAS#	387867-13-2
Inchi	InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h6,12,16,18-19H,4-5,7-11H2,1-3H3/t16-,18-,19-,20-,21+/m0/s1
Inchi Key	VRRHHTISESGZFN-RKFFNLMFSA-N
SMILES	CC(=O)C1=CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
Size	100mg
Supplier Page	http://www.selleckchem.com/products/Tandutinib-(MLN518).html
Additional Information	https://file.selleck.cn/downloads/struct/Tandutinib-MLN518-chemical-structure-S1043.gif