Tenofovir alafenamide fumarate
Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
| Trivial name | TAF fumarate, GS-7340 fumarate |
| Catalog Number | S4428 |
| Molecular Formula | C28H30FN3O4 |
| CAS# | 379270-38-9 |
| Inchi | InChI=1S/C28H30FN3O4/c1-7-30-26(33)22-13-20-21(14-32(6)27(34)24(20)31-22)19-12-17(28(4,5)35)8-9-23(19)36-25-15(2)10-18(29)11-16(25)3/h8-14,31,35H,7H2,1-6H3,(H,30,33) |
| Inchi Key | OEDSFMUSNZDJFD-UHFFFAOYSA-N |
| SMILES | CCNC(=O)C1=CC2=C(N1)C(=O)N(C=C2C3=C(C=CC(=C3)C(C)(C)O)OC4=C(C=C(C=C4C)F)C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tenofovir-alafenamide-fumarate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s4428-tenofovir-alafenamide-fumarate-chemical-structure.gif |