Zaprinast
Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5). Zaprinast causes a significant increase in cGMP levels in myocytes. Zaprinast is a G protein-coupled receptor 35 (GPR35) agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.
| Trivial name | M&B 22948 |
| Catalog Number | E7369 |
| Molecular Formula | C9H16ClN3O2 |
| CAS# | 37762-06-4 |
| Inchi | InChI=1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14) |
| Inchi Key | GQYIWUVLTXOXAJ-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)NC(=O)N(CCCl)N=O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/zaprinast.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7369-zaprinast-chemical-structure-tube.png |