Zaprinast

Zaprinast is a cyclic-GMP phosphodiesterase inhibitor with selectivity for PDE6, 5, 11 and 9 (IC50 = 0.15, 0.76, 12.0 and 29.0 μM, respectively). C-GMP acts as a mediator of signal transduction that relaxes vascular smooth muscles and increases blood flow. Therefore zaprinast exhibits vasodilating, relaxant, and diuretic effects. Zaprinast also acts as a putative GPR35 agonist.

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Catalog Number	37762-06-4
Alternative Name(s)	2-(2-Propyloxyphenyl)-8-azapurin-6-one; 5-(2-propoxyphenyl)-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one
Molecular Formula	C13H13N5O2
CAS#	37762-06-4
Purity	≥99%
Inchi	InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)
Inchi Key	REZGGXNDEMKIQB-UHFFFAOYSA-N
Size	Please inquire
Supplier Page	https://www.bocsci.com/zaprinast-cas-37762-06-4-item-20185.html