Maraviroc
Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.
| Trivial name | UK-427857 |
| Catalog Number | S2003 |
| Molecular Formula | C29H41F2N5O |
| CAS# | 376348-65-1 |
| Inchi | InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23?,24?,25?,26-/m0/s1 |
| Inchi Key | GSNHKUDZZFZSJB-ILVMPNSOSA-N |
| SMILES | CC1=NN=C(N1C2CC3CCC(C2)N3CCC(C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Maraviroc.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Maraviroc-chemical-structure-S2003.gif |