Maraviroc
Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.
| Trivial name | UK-427857 |
| Catalog Number | S2003 |
| Molecular Formula | C25H22N2O2 |
| CAS# | 376348-65-1 |
| Inchi | InChI=1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29) |
| Inchi Key | WVSBGSNVCDAMCF-UHFFFAOYSA-N |
| SMILES | C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=C3C=C(C=N4)C5=CC=CC=C5)C(=O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Maraviroc.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Maraviroc-chemical-structure-S2003.gif |