PIK-75
PIK-75 is a reversible DNA-PK and p110α-selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC50=1.3 μM). PIK-75 induces apoptosis.
| Catalog Number | E7171 |
| Molecular Formula | C13H17NO |
| CAS# | 372196-67-3 |
| Inchi | InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+ |
| Inchi Key | DNTGGZPQPQTDQF-XBXARRHUSA-N |
| SMILES | CCN(C1=CC=CC=C1C)C(=O)C=CC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pik-75.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7171-pik-75-chemical-structure-tube.png |