IC-87114
IC-87114 is a selective PI3Kδ inhibitor with IC50 of 0.5 μM in a cell-free assay, 58-fold more selective for PI3Kδ than PI3Kγ, and over 100-fold more selective than PI3Kα/β.
Trivial name | N/A |
Catalog Number | S1268 |
Molecular Formula | C22H19N7O |
CAS# | 371242-69-2 |
Inchi | InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22(29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9,11-12H,10H2,1-2H3,(H2,23,24,25) |
Inchi Key | GNWHRHGTIBRNSM-UHFFFAOYSA-N |
SMILES | CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C=NC5=C(N=CN=C54)N |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/IC-87114.html |
Additional Information | https://file.selleck.cn/downloads/struct/IC-87114-chemical-structure-S1268.gif |