Cuprizone
Cuprizone (biscyclohexanone oxalyldihydrazone) is a copper-chelating compound that forms stable, deep blue complexes with copper (II) ions, making it valuable for colorimetric assays to detect trace copper levels. It induces demyelination and schizophrenia-like behaviors in mice by interfering with copper-dependent enzymes, causing oxidative stress, and altering dopamine levels in critical brain regions.
Trivial name | biscyclohexanone oxalyldihydrazone |
Catalog Number | E7239 |
Molecular Formula | C21H26N2O7 |
CAS# | 370-81-0 |
Inchi | InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3 |
Inchi Key | UIAGMCDKSXEBJQ-UHFFFAOYSA-N |
SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/cuprizone.html |
Additional Information | https://file.selleck.cn/downloads/struct/E7239-Cuprizone-chemical-structure.png |