Mubritinib (TAK 165)

Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.

Price Not Available 10mM/1mL Mubritinib (TAK 165) Supplier Page
Trivial name N/A
Catalog Number S2216
Molecular Formula C25H22ClN5O2S
CAS# 366017-09-6
Inchi InChI=1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33)/t20-/m0/s1
Inchi Key GNMUEVRJHCWKTO-FQEVSTJZSA-N
SMILES CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/Mubritinib-TAK-165.html
Additional Information https://file.selleck.cn/downloads/struct/Mubritinib-TAK-165-chemical-structure-S2216.gif