Mubritinib (TAK 165)
Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.
Trivial name | N/A |
Catalog Number | S2216 |
Molecular Formula | C25H22ClN5O2S |
CAS# | 366017-09-6 |
Inchi | InChI=1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33)/t20-/m0/s1 |
Inchi Key | GNMUEVRJHCWKTO-FQEVSTJZSA-N |
SMILES | CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Mubritinib-TAK-165.html |
Additional Information | https://file.selleck.cn/downloads/struct/Mubritinib-TAK-165-chemical-structure-S2216.gif |