Mubritinib (TAK 165)
Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.
Trivial name | N/A |
Catalog Number | S2216 |
Molecular Formula | C20H20N2O4 |
CAS# | 366017-09-6 |
Inchi | InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22) |
Inchi Key | CJLMANFTWLNAKC-UHFFFAOYSA-N |
SMILES | COC1=CC(=CC(=C1OC)OC)C2=C(N=CC(=C2)C3=CC(=CC=C3)O)N |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/Mubritinib-TAK-165.html |
Additional Information | https://file.selleck.cn/downloads/struct/Mubritinib-TAK-165-chemical-structure-S2216.gif |