Mubritinib (TAK 165)
Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.
Trivial name | N/A |
Catalog Number | S2216 |
Molecular Formula | C25H23F3N4O2 |
CAS# | 366017-09-6 |
Inchi | InChI=1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+ |
Inchi Key | ZTFBIUXIQYRUNT-MDWZMJQESA-N |
SMILES | C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/Mubritinib-TAK-165.html |
Additional Information | https://file.selleck.cn/downloads/struct/Mubritinib-TAK-165-chemical-structure-S2216.gif |