A 419259
A 419259 (RK-20449) is a selective inhibitor of Src family kinase with IC50 of 9 nM for Src, <3 nM for Lck, and <3 nM for Lyn. It blocks the autophosphorylation of myeloid-specific kinases, disrupting key oncogenic signaling pathways.
| Trivial name | RK-20449 |
| Catalog Number | E7680 |
| Molecular Formula | C24H36O5 |
| CAS# | 364042-47-7 |
| Inchi | InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 |
| Inchi Key | PCZOHLXUXFIOCF-BXMDZJJMSA-N |
| SMILES | CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/a-419259.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7680-A-419259-chemical-structure.png |