Jatrorrhizine

Jatrorrhizine is a a novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb coptidis rhizome. Protects neuronal-like cells against H₂O₂-induced toxicity. JAT also displays neuroprotective effects against Aβ₂₅₋₃₅-induced injury via its antioxidative potential. Potential therapeutic for gastrointestinal disorders.

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Catalog Number ABA-022
Alternative Name(s) 7,8,13,13α-Tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium, Neprotin, Yatrorizine
CAS# 3621-38-3
Inchi InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1
Inchi Key MXTLAHSTUOXGQF-UHFFFAOYSA-O
SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC
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