2-Methoxyestradiol (2-MeOE2)
2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.
| Trivial name | NSC 659853, 2-ME2 |
| Catalog Number | S1233 |
| Molecular Formula | C19H26O3 |
| CAS# | 362-07-2 |
| Inchi | InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1 |
| Inchi Key | CQOQDQWUFQDJMK-SSTWWWIQSA-N |
| SMILES | CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/2-Methoxyestradiol(2ME2).html |
| Additional Information | https://file.selleck.cn/downloads/struct/2-Methoxyestradiol-chemical-structure-S1233.gif |