Triciribine (API-2)
Triciribine (API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
Trivial name | NSC 154020, VD-0002, vqd-002, TCN |
Catalog Number | S1117 |
Molecular Formula | C13H16N6O4 |
CAS# | 35943-35-2 |
Inchi | InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1 |
Inchi Key | HOGVTUZUJGHKPL-HTVVRFAVSA-N |
SMILES | CN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)CO)O)O)C(=N1)N |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/Triciribine.html |
Additional Information | https://file.selleck.cn/downloads/struct/Triciribine-chemical-structure-S1117.gif |