Cryptotanshinone (Tanshinone C)
Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis.
Catalog Number | S2285 |
Molecular Formula | C19H20O3 |
CAS# | 35825-57-1 |
Inchi | InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1 |
Inchi Key | GVKKJJOMQCNPGB-JTQLQIEISA-N |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/Cryptotanshinone.html |
Additional Information | https://file.selleck.cn/downloads/struct/Cryptotanshinone-chemical-structure-S2285.gif |