SB525334
SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.
| Trivial name | N/A |
| Catalog Number | S1476 |
| Molecular Formula | C21H21N5 |
| CAS# | 356559-20-1 |
| Inchi | InChI=1S/C21H21N5/c1-13-6-5-7-16(24-13)19-18(25-20(26-19)21(2,3)4)14-8-9-15-17(12-14)23-11-10-22-15/h5-12H,1-4H3,(H,25,26) |
| Inchi Key | DKPQHFZUICCZHF-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/SB-525334.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB525334-chemical-structure-S1476.gif |