Honokiol is a polyphenol found in the genus Magnolia. Honokiol acts as an Akt inhibitor and also inhibits NF-κB, displaying anti-inflammatory, antiangiogenic and antitumor properties. It results in inhibition of bone metastatic growth of human prostate cancer cells. Honokiol has obvious antioxidant and anti-aging effects, thus can be used in cosmetic material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products.