S-(5′-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor that is found in all living organisms.In Vitro: By donating the methyl group, sues that involves perchloric acid extraction has beenSAM is converted into S-adenosyl-L-homocysteine reported by She et al. Separation of SAM and (SAH).