Celastrol

Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson’s disease through activating mitophagy.

Price Not Available 50mg Celastrol Supplier Page
Trivial name NSC 70931, Tripterine
Catalog Number S1290
Molecular Formula C17H17N3O
CAS# 34157-83-0
Inchi InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21)
Inchi Key UJZDIKVQFMCLBE-UHFFFAOYSA-N
SMILES CCC1=CC=C(C=C1)NC(=O)NC2=CNC3=CC=CC=C32
Size 50mg
Supplier Page http://www.selleckchem.com/products/Celastrol.html
Additional Information https://file.selleck.cn/downloads/struct/Celastrol-chemical-structure-S1290.gif