Sunitinib malate
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.
| Trivial name | SU11248 malate |
| Catalog Number | S1042 |
| Molecular Formula | C4H9NO2 |
| CAS# | 341031-54-7 |
| Inchi | InChI=1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7) |
| Inchi Key | QCHPKSFMDHPSNR-UHFFFAOYSA-N |
| SMILES | CC(CN)C(=O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Sunitinib-Malate-(Sutent).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Sunitinib-Sutent-chemical-structure-S1042.gif |
