Auranofin
Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.
| Trivial name | SKF39162 |
| Catalog Number | S4307 |
| Molecular Formula | C20H34AuO9PS |
| CAS# | 34031-32-8 |
| SMILES | CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+] |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/auranofin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/auranofin-chemical-structure-s4307.gif |