JY-2 | MedChemExpress (MCE)
JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1].
| Trivial name | JY-2 |
| Catalog Number | HY-153347 |
| Research Area | Metabolic Disease |
| CAS# | 339103-05-8 |
| Purity | 99.75% |
| SMILES | ClC1=CC(Cl)=C(C2=NC(C3=CC=CC=N3)=NO2)C=C1 |
| PubChem Chemical Structure ID | 702923 |
| Size | 50 mg |
| Supplier Page | https://www.medchemexpress.com/jy-2.html |